Mr. Gambaryan was assigned to the investigation involving the corrupt members of the Baltimore Silk Road Task Force, as well as the investigation of Ripple Labs (XRP). Tigran is also the IRS-CI investigator who, together with HSI, arrested the operator of the world’s largest illegal BitTorrent download website, Kick Ass Torrents. Tigran lead the investigation and shutdown of BTC-e bitcoin exchange and the arrest of its operator Alexander Vinnik. Tigran also investigated Alphabay, Wall Street Marketplace, and Welcome2Video. More recently, Special Agent Gambaryan and his partners at the Federal Bureau of Investigations and the United States Secret Service investigated the “VIP” Twitter hack.

In 2015, Special Agent Gambaryan became the IRS-CI representative at the National Cyber Investigative Joint Task Force (NCIJTF), investigating matters related to national security and terrorism financing. Special Agent Gambaryan was one of the founding members of the NCIJTF Digital Currency Group.

In 2016, Special Agent Gambaryan joined the IRS-CI Washington DC Cyber Crimes Group (CCU). At the CCU, Special Agent Gambaryan investigated identity theft, digital currency laundering, distribution of child pornography, tax evasion, terrorism financing, nation-state hacking, and bank secrecy act violations.

In 2019, Special Agent Gambaryan was assigned to Europol as a liaison officer to the European Cybercrime Centre (EC3).

On September 20, 2021, Tigran Gambaryan became the Global Head of Intelligence and Investigations at Binance.com, and in 2022 he was promoted to lead Financial Crime Compliance.